CAS: 1185044-03-4

Applications A novel labelled pyrazolopyrimidine derivative, useful as cardiovascular agent. References Hucker, H., et al.: Drug Metab. Disp., 1, 721 (1973), Brogden, R., et al.: Drugs, 16, 97 (1978), Tulshian, D., et al.: J. Med. Chem., 36, 1210 (1993),

Pyrazole N-demethyl sildenafil-d3 is a synthetic impurity standard for drug development and research. It is used as an analytical reference material for the study of metabolism in humans, animals, and other species. Pyrazole N-demethyl sildenafil-d3 has been shown to inhibit the CYP2C9 enzyme from metabolizing sildenafil, leading to increased plasma levels of active sildenafil.