CAS: 1188264-72-3

Applications rac Desmethyl Citalopram-d4 Hydrobromide is the labeled analogue of rac Desmethyl Citalopram Hydrobromide (D230870), a metabolite of Citalopram (C505000), an inhibitor of serotonin (5-HT) uptake. Used as an antidepressant. References Gnerre, C., et al.: J. Pharm. Pharmacol., 53, 1125 (2001); Hagg, S., et al.: Br. J. Clin. Pharmacol., 51, 169 ( 2001); von Moltke, L., et al.: Drug Metab. Dispos., 29, 1102 (2001); Reis, M., et al.: Ther. Drug Monit., 27, 469 (2005)

Impurity USP Citalopram Related Compound D Applications rac Desmethyl Citalopram Hydrobromide is a metabolite of Citalopram, an inhibitor of serotonin (5-HT) uptake. Used as an antidepressant. References Gnerre, C., et al.: J. Pharm. Pharmacol., 53, 1125 (2001), Hagg, S., et al.: Br. J. Clin. Pharmacol., 51, 169 ( 2001), von Moltke, L., et al.: Drug Metab. Dispos., 29, 1102 (2001), Reis, M., et al.: Ther. Drug Monit., 27, 469 (2005),

Citalopram Related Compound D is an antiepileptic drug that belongs to the group of phenylpiperazine derivatives. It is a prodrug which is metabolized into escitalopram, its active form. Citalopram Related Compound D has been shown to have similar pharmacokinetic properties as escitalopram oxalate, with a half-life of about 3 hours. This drug has been shown to be effective in treating epilepsy and may also be used for the treatment of other neurological disorders such as Parkinson's disease and Alzheimer's disease. Citalopram Related Compound D is not indicated for use in patients who are taking carbamazepine or phenobarbital because it can increase plasma concentrations of these drugs.