CAS: 1189426-07-0

Glipizide-d11 is a liquid chromatography-mass spectrometry (LC-MS/MS) method for the quantitative determination of glipizide in human plasma. The validation process encompasses the evaluation of the linearity, accuracy, selectivity and robustness of the method. This method has been validated to ensure that it is suitable for use by other laboratories. Glipizide-d11 has been shown to be effective in treating diabetes mellitus type II and can be used to control blood glucose levels. It is classified as an antidiabetic agent and is used to lower blood sugar levels in patients with type II diabetes mellitus. Glipizide-d11 also has a low incidence of side effects on the heart, liver, or kidneys.

Applications Labelled Glipizide (G410225). A sulfonylurea hypoglycemic agent. Used as an antidiabetic. References Ambrogi, et al.: Arzneimittel-Forsch., 21, 200 (1971), Fuccella, et al.: J. Clin. Pharmacol., 13, 68 (1973), Brogden, R.N., et al.: Drugs, 18, 329 (1979), Lebovitz, H.E., et al.: Pharmacother., 5, 63 (1985)