CAS: 1189685-28-6

R,S equol 4'-sulfate sodium salt is a synthetic derivative of equol, which is a type of flavonoid metabolite. This compound is primarily sourced from the biotransformation of the isoflavone daidzein through gut microbiota activity. As a sulfate salt, it is more soluble in aqueous environments, which may facilitate its use in various biological contexts. The mode of action of R,S equol 4'-sulfate sodium salt involves its function as a selective estrogen receptor modulator (SERM). It can bind to estrogen receptors, particularly ER-beta, exhibiting both estrogenic and anti-estrogenic effects depending on the target tissue. This dual activity enables it to modulate hormonal responses finely and potentially influence pathways related to reproductive health and aging. R,S equol 4'-sulfate sodium salt is primarily used in research focusing on the health impacts of phytoestrogens, particularly in studying its influence on osteoporosis, cardiovascular health, and menopausal symptoms. Due to its structural similarity to endogenous estrogens, it provides a useful tool for exploring estrogen receptor involvement in various physiological processes.

Stability Moisture and Temperature Sensitive Applications (R,S)-Equol 4’-Sulfate is a sulfated metabolite of isoflavone Daidzein (D103500). References Heinonen, S., et al.: Anal. Biochem., 274, 211 (1999), Setchell, K., et al.: J. Nutr., 132, 3577 (2002), Thigpen, J., et al.: Comp. Med., 53, 607 (2003), Yee, S., et al.: Food Chem. Toxicol., 46, 2713 (2008),

(±)-Equol 4’-sulfate is a gut-mediated phase II metabolite of the isoflavonoid phytoestrogen (±)-equol .[1] It has been used as a standard for the