CAS 120138-50-3: Quinupristin
Formula:C53H67N9O10S
InChI:InChI=1/C53H67N9O10S/c1-6-37-50(68)61-23-11-14-38(61)51(69)59(5)40(26-32-16-18-36(19-17-32)58(3)4)52(70)62-28-35(30-73-43-29-60-24-20-33(43)21-25-60)42(64)27-39(62)47(65)57-45(34-12-8-7-9-13-34)53(71)72-31(2)44(48(66)55-37)56-49(67)46-41(63)15-10-22-54-46/h7-10,12-13,15-19,22,31,33,35,37-40,43-45,63H,6,11,14,20-21,23-30H2,1-5H3,(H,55,66)(H,56,67)(H,57,65)/t31-,35+,37?,38+,39?,40+,43-,44+,45+/m1/s1
Synonyms:- Quinupristin [USAN:INN]
- N-((6R,9S,10R,13S,15aS,18R,22S,24aS)-22-(p-(Dimethylamino)benzyl)-6-ethyldocosahydro-10,23-dimethyl-5,8,12,15,17,21,24-heptaoxo-13-phenyl-18-(((3S)-3-quinuclidinylthio)methyl)-12H-pyrido(2,1-f)pyrrolo(2,1-l)(1,4,7,10,13,16)oxapentaazacyclononadecin-9-yl)-3-hydroxypicolinamide
- Quinupristina
- Quinupristina [INN-Spanish]
- Quinupristine
- Quinupristine [INN-French]
- Quinupristinum
- Quinupristinum [INN-Latin]
- Unii-23Ow28Rs7P
- Virginiamycin S1, 4-(4-(dimethylamino)-N-methyl-L-phenylalanine)-5-(5-((1-azabicyclo(2.2.2)oct-3-ylthio)methyl)-4-oxo-L-2-piperidinecarboxylic acid)-, (S)-
- N-{18-[(1-azabicyclo[2.2.2]oct-3-ylsulfanyl)methyl]-22-[4-(dimethylamino)benzyl]-6-ethyl-10,23-dimethyl-5,8,12,15,17,21,24-heptaoxo-13-phenyldocosahydro-12H-pyrido[2,1-f]pyrrolo[2,1-l][1,4,7,10,13,16]oxapentaazacyclononadecin-9-yl}-3-hydroxypyridine-2-carboxamide
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Found 5 products.
Quinupristin
CAS:Formula:C53H67N9O10SPurity:97%Color and Shape:SolidMolecular weight:1022.2183800000013Quinupristin
CAS:Quinupristin, a macrolide-lincosamide-streptogramin antibiotic, inhibits protein synthesis in bacteria.Formula:C53H67N9O10SPurity:98.05% - 98.16%Color and Shape:SolidMolecular weight:1022.22Quinupristin
CAS:Quinupristin is a semi-synthetic antibiotic, which is derived from the natural compound pristinamycin IIA produced by the bacterium Streptomyces pristinaespiralis. It operates by binding to the 50S ribosomal subunit in bacterial cells, inhibiting protein synthesis and thus exerting a bacteriostatic effect. This mechanism effectively disrupts the growth and proliferation of susceptible bacteria. In clinical settings, Quinupristin is commonly used in combination with another antibiotic, Dalfopristin, forming a synergistic medication known as Synercid. This combination is particularly effective against Gram-positive bacteria, including those that are resistant to other antibiotic classes. It is often employed in the treatment of serious bacterial infections such as those caused by methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus faecium (VRE). The distinct mode of action of Quinupristin, coupled with its potent efficacy against resistant strains, underscores its importance in the antibiotic arsenal, particularly as antimicrobial resistance continues to rise globally.Formula:C53H67N9O10SPurity:Min. 95%Molecular weight:1,022.22 g/mol
