CAS 120363-13-5: Benzoic acid, 4-iodo-, 1,1-dimethylethyl ester

tert-Butyl 4-iodobenzoate

Applications 4-iodo substituted benzoic acid derivative used as a building block for the synthesis of various of biologically active compounds.

Tert-butyl 4-iodobenzoate is an aryl halide that can be used as an analog for tert-butyl benzoate. It is typically synthesized by the reaction of Grignard reagent with chloroiodobenzene in the presence of a base. The synthesis of tert-butyl 4-iodobenzoate is possible because it has a high solubility in organic solvents and at high concentrations, which makes it easier to extract and purify. Tert-butyl 4-iodobenzoate can be used to create architectures in monolayers, which are important for molecular recognition. This compound also has been used as a synthetic intermediate for other compounds.