CAS 1207-72-3: 10-Methylphenothiazine

10-Methylphenothiazine is a cation that has been found to have antioxidant properties. It is a radical with redox potentials of +1.7 and +0.5 V vs. NHE, respectively. 10-Methylphenothiazine also reacts with oxygen to form phenoxazine, which in turn reacts with hydrogen peroxide to produce the radical 2-hydroxy-1,4-benzoquinone. This radical can then react with other radicals to form stable products such as 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS). 10-Methylphenothiazine acts as a fluorescence probe for many reactions, including oxidation reactions and electron transfer reactions. The fluorescence intensity of 10-methylphenothiazine changes depending on the concentration of phenoxazine in solution and the reaction rate.

They are used in pharmaceutical manufacturing especially antipsychotic drugs. Also used as a stabilizer against polymerization of acrylates. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

10-Methylphenothiazine