CAS 121345-64-0: N-[2-(3,4-dimethoxyphenyl)ethyl]-N-methyl-3-(4-{[1-methyl-2-(propan-2-yl)-1H-indol-3-yl]sulfonyl}phenoxy)propan-1-amine

SR33805

SR33805 is a synthetic investigational compound, which is primarily derived from chemical synthesis with potential cardiovascular applications. This compound functions as a calcium channel antagonist, targeting specific ion channels that regulate the influx of calcium ions in cardiac and smooth muscle cells. By modulating these ion channels, SR33805 can affect muscle contractility and vascular tone. The compound is mainly utilized in experimental settings to explore its effects on cardiovascular physiology and pathology. Researchers employ SR33805 to study its potential in managing conditions such as hypertension, angina, and cardiac arrhythmias. The compound's ability to interact with calcium channels makes it a valuable tool in understanding cardiovascular diseases and developing new therapeutic strategies. Although still under investigation, SR33805 offers insights into the modulation of ion channels and their implications in cardiovascular medicine.

SR33805 is a potent antagonist of Ca2+ channel(EC50s of 4.1 nM and 33 nM in depolarized and polarized conditions, respectively)