CAS: 1215281-19-8

YK-3-237

YK 3-237 is a potent inhibitor of the p21 protein, which is involved in cell cycle regulation and apoptosis. YK 3-237 has been shown to inhibit the transcriptional activity of transcription polymerase chain (PCR) by binding to the RNA polymerase II enzyme. This inhibition prevents mda-mb-231 breast cancer cells from proliferating and induces apoptosis. YK 3-237 also inhibits epidermal growth factor, which may be involved in the development of cancerous tumors. It has been observed that YK 3-237 blocks angiogenesis, hiv infection and monoclonal antibody production in vitro.

YK-3-237 (B-[2-Methoxy-5-[(1E)-3-oxo-3-(3,4,5-trimethoxyphenyl)-1-propen-1-yl]phenyl]boronic acid) reduces acetylation of mtp53 and exhibits anti-proliferative