CAS 121577-32-0: Gatifloxacinacid

Gatifloxacin hydrochloride is a fluoroquinolone antibiotic, which is synthesized chemically from quinolone compounds. It exhibits its mode of action by inhibiting bacterial DNA gyrase and topoisomerase IV, essential enzymes responsible for DNA replication and transcription processes in bacteria. This disruption of DNA processes leads to bacterial cell death, making it effective against a wide range of Gram-positive and Gram-negative bacteria. Gatifloxacin hydrochloride is commonly utilized in the treatment of various bacterial infections, such as respiratory tract infections, urinary tract infections, and conjunctivitis. Its broad-spectrum activity makes it valuable in clinical settings, especially in cases of mixed bacterial infections or resistance to other antibiotics. Gatifloxacin's efficacy and pharmacokinetic properties allow for both oral and ophthalmic application, providing flexibility in therapeutic approaches. Despite its effectiveness, its use may be limited by concerns over side effects and resistance development, necessitating careful consideration in clinical applications.

Gatifloxacin hydrochloride, a fourth-gen fluoroquinolone antibiotic, blocks bacterial DNA rotase and topoisomerase IV.

Gatifloxacin hydrochloride

Gatifloxacin acid