CAS 121839-78-9: (αR)-α-Methyl-4-(2-methylpropyl)benzeneacetamide

(-)-Ibuprofenamide is a chiral pharmaceutical compound, derived from the widely used nonsteroidal anti-inflammatory drug (NSAID) ibuprofen. It is obtained through the amide formation from the carboxylic acid group of ibuprofen, which involves chemical synthesis methods that focus on retaining the stereochemistry of the parent molecule. The mode of action of (-)-Ibuprofenamide involves the modulation of enzyme activity within the cyclooxygenase (COX) pathways, specifically targeting COX-1 and COX-2 enzymes. By inhibiting these enzymes, (-)-Ibuprofenamide reduces the synthesis of pro-inflammatory prostaglandins, leading to potential analgesic and anti-inflammatory effects. In terms of applications, (-)-Ibuprofenamide is primarily explored in scientific research, where its efficacy and safety profile can be compared against conventional ibuprofen. The chiral nature of (-)-Ibuprofenamide makes it a subject of interest for studies aiming to analyze the enantiomer-specific effects in pharmacology, which can contribute to the development of more targeted therapeutic agents. This product is utilized mainly in experimental models and controlled studies investigating the pharmacokinetics and pharmacodynamics associated with modified NSAID derivatives.

(-)-Ibuprofenamide is an amide prodrug of Ibuprofen with anti-inflammatory activity.