CAS: 1219794-69-0

Applications Phenylbutazone(diphenyl-d10) is the isotope labelled analog of Phenylbutazone (P319570); a non-steroidal anti-inflammatory compound and an inhibitor of cyclooxygenase that is also a substrate for peroxidation by cyclooxygenase. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Ali, S.L., Anal. Profiles Drug Subs., 11, 483 (1982); Hughes, M.F., et al.: Mol. Pharmacol., 34, 186 (1988)

Phenylbutazone is a nonsteroidal anti-inflammatory drug (NSAID) that is used to relieve pain and inflammation in animals. It belongs to the group of nonsteroidal drugs, which are competitive inhibitors of cyclooxygenase enzymes. Phenylbutazone also has an antirheumatic effect and can be used for the treatment of arthritis in horses. This drug has been shown to be effective against carprofen-sensitive strains of bacteria such as Salmonella enterica and Escherichia coli. Phenylbutazone is a weak acid that ionizes at physiological pH, so it does not bind well to proteins in the matrix. The presence of acidic compounds in the matrix can cause interference with this technique, which may lead to false results.