CAS: 1219795-48-8

Applications Isotope labelled 4-(Trifluoromethyl)aniline, a substituted aniline derivative that exerts special hematotoxicity on the red blood cells and induce leukocytosis. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Weber, W., et al.: Pharmacol. Rev., 37, 25 (1985), Hein, D., et al.: Carcinogenesis, 14, 1633 (1993), Payton, M., et al.: Microbiology, 147, 1137 (2001), Mushtaq, A., et al.: J. Biol. Chem., 277, 12175 (2002),

4-(Trifluoromethyl)aniline is a non-aromatic amine that can be prepared by the elimination of propiophenone. It can also be synthesized with a Grignard reagent and iminium ion. 4-(Trifluoromethyl)aniline undergoes an electrophilic substitution reaction with triflic acid to form an iminium ion, which then reacts with a nucleophile to form an imine. The mechanism for this reaction is unclear and has been studied extensively using magnetic resonance spectroscopy (NMR), x-ray diffraction data, and other techniques.