CAS 122188-02-7: Methyl 1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetate

The tetrahydropyran is an organic compound with the molecular formula CH3CH2CH2C(O)CH2OH. It is a colorless liquid that is soluble in water and polar organic solvents. The compound can be prepared by reacting acetonitrile with trimethyl borate: The reaction products of this process are among other things, 1,8-diethyl-1,3,4,9-tetrahydro-pyrano[3,4-b]indole-1-acetic acid methyl ester (DETPA). DETPA has been used as a neutralizing agent in the treatment of textile dyeing effluents and as a flow rate controller in metering pumps. Biological properties of DETPA include antipyretic properties and acid catalytic activity. One of the impurities found in DETPA is 3-(2'-hydroxyethoxy)propionic acid which can be removed by treatment

Impurity Etodolac EP Impurity K Applications 1,8-Diethyl-1,3,4,9-tetrahydro-pyrano[3,4-b]indole-1-acetic Acid Methyl Ester (Etodolac EP Impurity K) is a derivative of Etodolac. References Caldwell, J., et al.: Biochem. Pharmacol., 37, 105 (1988), Drummer, O., et al.: J. Anal. Toxicol., 17, 225 (1993)