CAS: 1224567-46-7

653-47 is a synthetic peptide that binds to the extracellular domain of the human angiotensin II type 1 receptor. It has been shown to be an inhibitor of protein interactions and activator of ligand-receptor interactions. 653-47 is used as a research tool for studying the role of angiotensin II receptors in cell biology and as a reagent for antibody production. 653-47 is also used as an ion channel blocker. This peptide has high purity, and can be obtained from many manufacturers.

653-47 hydrochloride boosts CREB inhibition by 666-15 and weakly inhibits CREB itself (IC50: 26.3 μM).

653-47 hydrochloride