CAS 122666-87-9: L-Tyrosine disodium salt, dihydrate

Tyrosine is a polar, naturally occurring, non-essential amino acid. It is used as a cell culture media component for the commercial biomanufacture of therapeutic recombinant proteins and monoclonal antibodies. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

L-Tyrosine is a biologically active natural amino acid that is used in the synthesis of proteins. It is also an intermediate in the synthesis of melanin. L-Tyrosine has been shown to be effective in clinical studies for the treatment of tyrosinase deficiency, which leads to increased susceptibility to skin cancer. L-Tyrosine disodium salt dihydrate (LTD) has been shown to have a hemolytic activity and can be used as an alternative to hydroquinone as a skin-lightening agent. It is also used as a substrate for diphenolase, which catalyzes the conversion of 4,4'-dihydroxydiphenyl ethers into diphenols, such as 4,4'-dihydroxydiphenylether (DDPE). L-Tyrosine disodium salt dihydrate can also inhibit gossypol derivatives by competitive inhibition and may be useful in treatments for prostate cancer.

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