CAS: 1229018-87-4

TPN171 is a synthetic drug that has been shown to increase blood flow to the penis in humans. It is a prodrug of sildenafil, which is converted by cytochrome P450 in the liver to the active form. TPN171 has been found to be more potent than sildenafil and was able to inhibit platelet activation, suggesting it could have potential for use in cardiovascular diseases.

TPN171

TPN171 is potent PDE5 inhibitor with subnanomolar potency for PDE5 and good selectivity over PDE6, which has the potential for the treatment of pulmonary