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CAS 1229194-11-9: Ethanediamide, N1-(5-chloro-2-pyridinyl)-N2-[(1S,2R,4S)-4-[(dimethylamino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]-, 4-methylbenzenesulfonate, hydrate (1:1:1)
Formula:C24H30ClN7O4S·C7H8O3S·H2O
InChI:InChI=1S/C24H30ClN7O4S.C7H8O3S.H2O/c1-31(2)24(36)13-4-6-15(27-20(33)21(34)30-19-7-5-14(25)11-26-19)17(10-13)28-22(35)23-29-16-8-9-32(3)12-18(16)37-23;1-6-2-4-7(5-3-6)11(8,9)10;/h5,7,11,13,15,17H,4,6,8-10,12H2,1-3H3,(H,27,33)(H,28,35)(H,26,30,34);2-5H,1H3,(H,8,9,10);1H2/t13-,15-,17+;;/m0../s1
InChI key:InChIKey=PSMMNJNZVZZNOI-SJILXJHISA-N
SMILES:N(C(=O)C1=NC2=C(S1)CN(C)CC2)[C@H]3[C@@H](NC(C(NC4=CC=C(Cl)C=N4)=O)=O)CC[C@H](C(N(C)C)=O)C3.S(=O)(=O)(O)C1=CC=C(C)C=C1.O
Synonyms:- Edoxaban Tosylate Monohydrate
- Edoxaban tosylate hydrate
- Edoxaban4-methylbenzenesulfonate, hydrate (1:1:1)
- Ethanediamide, N<sup>1</sup>-(5-chloro-2-pyridinyl)-N<sup>2</sup>-[(1S,2R,4S)-4-[(dimethylamino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]-, 4-methylbenzenesulfonate, hydrate (1:1:1)
- N-(5-Chloropyridin-2-yl)-N′-((1S,2R,4S)-4-[(dimethyl amino)carbonyl]-2-[[(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl)ethanediamide p-toluenesulfonate monohydrate
- N-(5-Chloropyridin-2-yl)-N′-[(1S,2R,4S)-4-[(dimethylamino)carbonyl]-2-[[(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]ethanediamide mono(p-toluenesulfonate) monohydrate
- Ethanediamide, N1-(5-chloro-2-pyridinyl)-N2-[(1S,2R,4S)-4-[(dimethylamino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]-, 4-methylbenzenesulfonate, hydrate (1:1:1)
- Edoxaban tosylate monohydrate(for Edoxaban)
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Found 7 products.
Ethanediamide, N1-(5-chloro-2-pyridinyl)-N2-[(1S,2R,4S)-4-[(dimethylamino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]-, 4-methylbenzenesulfonate, hydrate (1:1:1)
CAS:Formula:C31H40ClN7O8S2Purity:97%Color and Shape:SolidMolecular weight:738.2744Edoxaban Tosylate Monohydrate
CAS:Edoxaban Tosylate MonohydratePurity:≥98%Molecular weight:738.27g/molEdoxaban tosylate hydrate
CAS:Edoxaban tosylate hydrate is an anticoagulant that inhibits the activity of thrombin and factor Xa. It has a long half-life and does not undergo significant first-pass metabolism in the liver. Edoxaban tosylate hydrate is used for the prevention of stroke in patients with atrial fibrillation. It can be administered orally or by intravenous infusion, and its effect is monitored by measuring levels of the natriuretic peptide NT-proBNP. Edoxaban tosylate hydrate has a low potential for drug interactions, which may be due to its low protein binding affinity (less than 10%). This drug also inhibits P-glycoprotein, which may lead to bleeding complications.Formula:C24H30ClN7O4S·C7H8O3S·H2OPurity:Min. 95%Molecular weight:738.28 g/molEdoxaban Tosylate Monohydrate
CAS:Edoxaban(DU-176) is an oral factor Xa (FXa) inhibitor in clinical development for stroke prevention.Formula:C31H40ClN7O8S2Purity:99.86% - 99.91%Color and Shape:SolidMolecular weight:738.27N1-(5-Chloropyridin-2-Yl)-N2-((1S,2R,4S)-4-(Dimethylcarbamoyl)-2-(5-Methyl-4,5,6,7-Tetrahydrothiazolo[5,4-C]Pyridine-2-Carboxamido)Cyclohexyl)Oxalamide 4-Methylbenzenesulfonate Hydrate
CAS:N1-(5-Chloropyridin-2-Yl)-N2-((1S,2R,4S)-4-(Dimethylcarbamoyl)-2-(5-Methyl-4,5,6,7-Tetrahydrothiazolo[5,4-C]Pyridine-2-Carboxamido)Cyclohexyl)Oxalamide 4-Methylbenzenesulfonate HydrateMolecular weight:738.27g/molEdoxaban Tosylate Monohydrate
CAS:Applications Edoxaban is an anticoagulant drug which acts as a direct factor Xa inhibitor. References Ruff, C., et al.: Am. Heart J., 160, 635 (2010); Ogata, K., et al.: J. Clin. Pharm., 50, 73 (2010)Formula:C31H38ClN7O7S2•xH2OColor and Shape:White To Off-WhiteMolecular weight:720.26
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