CAS: 122929-22-0

2',3'-Dideoxy-2'-fluorouridine (ddFU) is a nucleoside that is used in the treatment of cancer. It inhibits DNA synthesis and cellular proliferation by blocking the activity of DNA polymerase, which is an enzyme required for DNA replication. 2',3'-Dideoxy-2'-fluorouridine has been shown to be an effective agent against leukemias, lymphomas, and solid tumors. In addition, this compound is being studied for its potential use as a radiation sensitizer to enhance the therapeutic effect of radiation therapy in the treatment of cancer.