CAS 123-66-0: Ethyl hexanoate

Applications Ethyl Caproate is used in the synthesis of novel EP2/EP4 dual agonist of γ-lactam prostaglandin E1 analogs. Also used as a chemical reagent in the synthesis of PPARα antagonists in the treatment of metabolic diseases. References Kambe, T. et al. Bioorg. Med. Chem. Lett., 22, 396 (2012); Ammazzalorso, A. et al.: Bioorg. Med. Chem. Lett., 21, 4869 (2011);

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Ethyl caproate is a type of ester that is used in the synthesis of other chemicals. Ethyl caproate has been shown to be an optimum concentration for water permeability and can be used as a model system for the study of HIV infection. This compound binds to RNA polymerase II, which is required for the transcription of DNA into RNA. In addition, it inhibits the polymerase chain reaction by binding to the enzyme’s active site and prevents DNA replication. The ethyl decanoate monomer reacts with hydrogen fluoride in a preparative high-performance liquid chromatography (HPLC) method to produce ethyl caproate as a pure product. Ethyl caproate also has biochemical properties such as inhibition of protein synthesis and induction of apoptosis.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.