CAS: 1242422-09-8

SSTC3 is a recombinant protein that inhibits the PI3K/Akt pathway. This pathway, which is involved in regulating cell proliferation, is often activated by cancer stem cells. The inhibition of this pathway leads to the death of cancer cells and can be used for the treatment of cancers, such as brain cancer. SSTC3 has been shown to be effective against human tumor cells in vitro and in vivo. In addition, SSTC3 has also been shown to reduce the incidence of diabetes mellitus type 2 in diabetic patients by its ability to inhibit insulin resistance. Clinical data on SSTC3 is limited but promising.

SSTC3 is a casein kinase 1α (CK1α) activator with potential antitumor activity that inhibits WNT signaling.