CAS: 1246303-04-7

NBD 18:0 ceramide is a synthetic fluorescent lipid analogue, which is derived from the naturally occurring sphingolipid, ceramide. This product is characterized by the attachment of a nitrobenzoxadiazole (NBD) fluorophore to the ceramide backbone, allowing it to serve as a tool for visualizing and studying lipid dynamics within biological membranes. The mode of action of NBD 18:0 ceramide involves its incorporation into lipid bilayers, where it can mimic natural ceramides and participate in membrane-related processes, while the attached NBD group provides a fluorescent signal. This fluorescence facilitates the tracking and analysis of ceramide distribution, interaction with other membrane constituents, and roles in cellular signaling pathways. NBD 18:0 ceramide is utilized in various applications, including studies on membrane organization, lipid trafficking, and sphingolipid metabolism. Its ability to integrate into cell membranes without significantly altering their native properties makes it a valuable tool for researchers investigating the functional roles of ceramides in health and disease. Through fluorescence microscopy and spectroscopy, scientists can gain insights into the dynamic behavior of lipids in live cells and model systems.