
CAS 125464-42-8: Saclofen
Formula:C9H12ClNO3S
InChI:InChI=1S/C9H12ClNO3S/c10-9-3-1-7(2-4-9)8(5-11)6-15(12,13)14/h1-4,8H,5-6,11H2,(H,12,13,14)
InChI key:InChIKey=JYLNVJYYQQXNEK-UHFFFAOYSA-N
SMILES:C(CS(=O)(=O)O)(CN)C1=CC=C(Cl)C=C1
Synonyms:- (RS)-3-amino-2-(4-chlorophenyl)propylsulfonic acid
- 3-Amino-2-(4-chlorophenyl)propane-1-sulfonic acid
- Benzeneethanesulfonic acid, β-(aminomethyl)-4-chloro-
- β-(Aminomethyl)-4-chlorobenzeneethanesulfonic acid
- Saclofen
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Found 7 products.
Benzeneethanesulfonic acid, β-(aminomethyl)-4-chloro-
CAS:Formula:C9H12ClNO3SPurity:98%Color and Shape:SolidMolecular weight:249.7145Saclofen
CAS:Saclofen is a GABA analog and GABAB receptor antagonist, useful for studying inhibitory brain signals. IC50: 7.8 μM.Formula:C9H12ClNO3SPurity:99.17%Color and Shape:White Crystalline SolidMolecular weight:249.71Saclofen
CAS:M02490 - SaclofenFormula:C9H12ClNO3SPurity:>99%Color and Shape:SolidMolecular weight:249.7100067138672Saclofen
CAS:Controlled ProductApplications Saclofen is a GABABR antagonist that has been shown to reduced leukocyte migration and increase Fos expression in T7-T11 sympathetic preganglionic neurons References Yoon, S., et. al.: Neuropharmacology, 53, 677 (2007)Formula:C9H12ClNO3SColor and Shape:NeatMolecular weight:249.7143-Amino-2-(4-chlorophenyl)propane-1-sulfonic acid
CAS:3-Amino-2-(4-chlorophenyl)propane-1-sulfonic acid (ACPS) is a potent antagonist of the cholinergic receptors, which are involved in the transmission of nerve impulses to muscles and glands. It blocks acetylcholine release from cholinergic nerves and inhibits the activity of acetylcholinesterase. ACPS has been shown to be effective in treating autoimmune diseases such as rheumatoid arthritis and multiple sclerosis. 3-Amino-2-(4-chlorophenyl)propane-1-sulfonic acid also has been shown to have effects on dopamine, which is a neurotransmitter that affects mood, attention, learning, and sleep. The drug binds to toll like receptor 4 (TLR4), which is an immune cell receptor that recognizes bacteria or bacterial products and activates the innate immune system. The TLR4 receptor is found on brain cells called microglia that play an important roleFormula:C9H12ClNO3SPurity:Min. 95%Molecular weight:249.72 g/mol