CAS: 125559-00-4

Applications A sulfhydryl and amino reactive heterobifunctional protein crosslinking reagent. References Yoshitake, S., et al.: Eur. J. Biochem., 101, 395 (1979)

N-Succinimidyl 6-[[4-(maleimidomethyl)cyclohexyl]carboxamido]caproate is a spacer, conjugating, maleimide, and linker compound. It has been used as a conveyor in the synthesis of protein conjugates, as well as to activate sulfhydryl groups on proteins for use in labeling. The maleimide group can be activated with sulfhydryl groups on proteins and then conjugated to another protein molecule. This process is known as activation. Activation is beneficial because it allows the site-specific attachment of molecules without affecting the activity of the protein. The linking process also does not require any additional chemical steps or purification steps, which saves time and money.