CAS: 1257705-09-1

GS-829845 is a JAK1 inhibitor, the main component of the active metabolite of Filgotinib, which is approximately 10-fold less potent and has a longer half-life

GS-829845

5-[4-[(1,1-Dioxo-1,4-thiazinan-4-yl)methyl]phenyl]-[1,2,4]triazolo[1,5-a]pyridin-2-amine is a high quality reagent which is used as a useful intermediate for the preparation of fine chemicals. It is an important building block in the synthesis of compounds with a wide range of applications. 5-[4-[(1,1-Dioxo-1,4-thiazinan-4-yl)methyl]phenyl]-[1,2,4]triazolo[1,5-a]pyridin-2-amine has been reported to be active against bacteria and fungi. The compound has also shown to have antiinflammatory activities and has been shown to inhibit prostaglandin synthesis.