Angiotensin IV is a peptide that plays a significant role in the regulation of blood pressure and fluid balance in the body. It is derived from the angiotensin II peptide through enzymatic cleavage. Angiotensin IV is known to interact with specific receptors, influencing various physiological processes, including vasodilation and modulation of renal function. The substance is characterized by its relatively small molecular size and specific amino acid sequence, which is crucial for its biological activity. It is primarily studied in the context of cardiovascular health and potential therapeutic applications in conditions such as hypertension and heart failure. Additionally, Angiotensin IV has been investigated for its neuroprotective properties and its role in cognitive functions. Its CAS number, 12676-15-2, is a unique identifier that facilitates the identification and study of this compound in scientific literature and databases. Overall, Angiotensin IV is an important molecule in the renin-angiotensin system, contributing to various physiological and pathological processes.

ANGIOTENSIN IV

12676-15-2: (2S)-2-[[(2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-amino-3-methylbutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-3-(3H-imidazol-4-yl)propanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid, angiotensin III, 1-desarginine-, Ang IV, Angiotensin II (3-8), Angiotensin IV trifluoroacetate salt

Angiotensin IV trifluoroacetate is an active analogue of angiotensin. It has been shown to have a high affinity for AT1 receptors and is able to enhance the uptake of angiotensin in proximal tubules, which may be due to its ability to bind DNA. Angiotensin IV trifluoroacetate has also been shown to have beneficial effects on skin cells, such as the reduction of skin inflammation and alleviation of pain. Angiotensin IV trifluoroacetate has shown anti-inflammatory activities, which may be due to its ability to reduce pro-inflammatory cytokines such as IL-6 and TNF-α. This drug also binds to the CD4 receptor, thereby inhibiting inflammatory responses in autoimmune diseases.

Angiotensin IV trifluoroacetate

Angiotensin II (3-8), human is a less effective agonist at the angiotensin AT1 receptor.

CAS 12676-15-2: ANGIOTENSIN IV

Angiotensin IV trifluoroacetate

Ref: 3D-MAA67615

Angiotensin II (3-8), human

Ref: TM-T5824