CAS 127-06-0: Acetone, oxime

Applications Acetone oxime was one of the reagents used as a part of preparation of arylbenzoxazoles as potent and selective estrogen receptor-β ligands. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Malamas, M., et al.: J. Med. Chem., 47, 5021 (2004)

It is an intermediate used in organic synthesis and in agriculture. It is also an important raw material. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Propan-2-one oxime is a cyclase inhibitor that has been shown to be effective against infectious diseases. It binds to the active site of cyclases and blocks the formation of the reactive intermediate, which is required for the conversion of acetone to water vapor. Propan-2-one oxime has been shown to inhibit human serum cyclase and xanthine oxidase in vitro. This compound also inhibits pluripotent cells from differentiating into erythrocytes, hepatocytes, or muscle cells, but does not inhibit differentiation of other cell types such as fibroblasts or epithelial cells. Propan-2-one oxime can be used in conjunction with anhydrous sodium acetate and methyl ethyl ketone to produce a Langmuir adsorption isotherm that can be used for calculating the surface area of adsorbent materials.

Propan-2-one oxime

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.