CAS 127-30-0: Lasiocarpine, N-oxide
Formula:C21H33NO8
InChI:InChI=1S/C21H33NO8/c1-7-13(2)18(23)30-16-9-11-22(27)10-8-15(17(16)22)12-29-19(24)21(26,14(3)28-6)20(4,5)25/h7-8,14,16-17,25-26H,9-12H2,1-6H3/b13-7-/t14-,16+,17-,21+,22?/m1/s1
InChI key:InChIKey=AABILZKQMVKFHP-LZUZPLOVSA-N
SMILES:O=N12[C@@]([C@@H](OC(/C(=C\C)/C)=O)CC1)(C(COC([C@@]([C@H](OC)C)(C(C)(C)O)O)=O)=CC2)[H]
Synonyms:- 2-Butenoic acid, 2-methyl-, (1S,7aR)-7-(((2R)-2,3-dihydroxy-2-((1S)-1-methoxyethyl)-3-methyl-1-oxobutoxy)methyl)-2,3,5,7a-tetrahydro-4-oxido-1H-pyrrolizin-1-yl ester, (2Z)-
- 2-Butenoic acid, 2-methyl-, (1S,7aR)-7-[[(2R)-2,3-dihydroxy-2-[(1R)-1-methoxyethyl]-3-methyl-1-oxobutoxy]methyl]-2,3,5,7a-tetrahydro-4-oxido-1H-pyrrolizin-1-yl ester, (2Z)-
- 2-Butenoic acid, 2-methyl-, 7-[[2,3-dihydroxy-2-(1-methoxyethyl)-3-methyl-1-oxobutoxy]methyl]-2,3,5,7a-tetrahydro-1H-pyrrolizin-1-yl ester, N-oxide, [1S-[1α(Z),7[S*(R*)],7aα]]-
- 7-({[2,3-dihydroxy-2-(1-methoxyethyl)-3-methylbutanoyl]oxy}methyl)-4-oxido-2,3,5,7a-tetrahydro-1H-pyrrolizin-1-yl (2E)-2-methylbut-2-enoate (non-preferred name)
- Brn 0060898
- Lasiocarpine oxide
- Lasiocarpine, 4-oxide
- Lasiocarpine N-oxide
- 4-21-00-02054 (Beilstein Handbook Reference)
- Lasiocarpine, N-oxide
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Found 11 products.
Lasiocarpine N-Oxide
CAS:Controlled ProductFormula:C21H33NO8Color and Shape:NeatMolecular weight:427.49Lasiocarpine N-Oxide-d3
CAS:Controlled ProductFormula:C21D3H30NO8Color and Shape:NeatMolecular weight:430.507Lasiocarpine n-oxide
CAS:Natural alkaloidFormula:C21H33NO8Purity:≥ 95.0 % (HPLC)Color and Shape:PowderMolecular weight:427.5Lasiocarpine N-oxide
CAS:Lasiocarpine N-oxide is a natural compound found to be higher in many tea bags, herbal drugs and honey by mass spectrometry.Formula:C21H33NO8Color and Shape:SolidMolecular weight:427.494Lasiocarpine N-oxide
CAS:Lasiocarpine N-oxide is a pyrrolizidine alkaloid, which is a naturally occurring compound derived primarily from plant sources in the Boraginaceae and Asteraceae families. These compounds are characterized by a N-oxide moiety attached to the basic lasiocarpine structure. The mode of action involves metabolic activation in the liver to form highly reactive intermediates, which subsequently interact with cellular macromolecules such as DNA and proteins. This leads to hepatotoxicity, characterized by liver damage and potential carcinogenic effects. In scientific research, Lasiocarpine N-oxide is investigated for its toxicological properties, serving as a model compound to study the metabolic pathways and mechanisms underlying pyrrolizidine alkaloid-induced liver toxicity. It also aids in exploring preventive measures and therapeutic interventions for alkaloid poisoning. Due to its potent biological effects, Lasiocarpine N-oxide is of interest in fields such as toxicology, pharmacology, and environmental health. Great care is warranted in handling and studying this compound, considering its potential health hazards.Formula:C21H33NO8Purity:Min. 95%Molecular weight:427.49 g/molLasiocarpine-N-oxide 100 µg/mL in Water
CAS:Controlled ProductFormula:C21H33NO8Color and Shape:Single SolutionMolecular weight:427.49
