Acetylsulfathiazole, with the CAS number 127-76-4, is a sulfonamide antibiotic that exhibits antibacterial properties. It is characterized by its sulfonamide functional group, which is essential for its mechanism of action, inhibiting bacterial growth by interfering with folic acid synthesis. The compound is typically a white to off-white crystalline powder, soluble in water and organic solvents, which facilitates its use in various formulations. Acetylsulfathiazole is primarily used in the treatment of bacterial infections, particularly those caused by susceptible strains of bacteria. Its pharmacological profile includes a relatively short half-life, necessitating multiple doses for effective therapeutic outcomes. Additionally, it may exhibit side effects common to sulfonamides, such as allergic reactions or gastrointestinal disturbances. Due to its specific action against bacteria, it has been utilized in both human and veterinary medicine, although its use has declined with the advent of more effective antibiotics. Proper handling and storage conditions are essential to maintain its stability and efficacy.

Acetylsulfathiazole

127-76-4: 2-(p-Acetamidobenzenesulfonamido)thiazole, AST, Acetamide, N-[4-[(2-thiazolylamino)sulfonyl]phenyl]-, Acetanilide, 4′-(2-thiazolylsulfamoyl)-, Acetylsulfathiazole, N-Acetylsulfathiazole, N-[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]acetamide, N-[4-[(2-Thiazolylamino)sulfonyl]phenyl]acetamide, N4-acetylsulfathiazole, N<sup>4</sup>-Acetylsulfathiazole, Sulfathiazole, acetyl-, p-Acetylamino-N-(2-thiazolyl)benzenesulfonamide

N-(4-(N-(Thiazol-2-yl)sulfamoyl)phenyl)acetamide

Applications N-Acetylsulfathiazole (~90%) is a metabolite of veterinary drugs found in urine. It is also an organic pollutant detected in the municipal wastewater.
References Kaufmann, A., et al.: Anal. Chim. Acta, 586, 13 (2007); Schymanski, E., et al.: Environ. Sci. Technol., 48, 1811 (2014);


N-Acetylsulfathiazole

Acetamide, N-[4-[(2-thiazolylamino)sulfonyl]phenyl]-

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CAS 127-76-4: Acetylsulfathiazole

N-(4-(N-(Thiazol-2-yl)sulfamoyl)phenyl)acetamide

Ref: 10-F694997

N-Acetylsulfathiazole

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Acetamide, N-[4-[(2-thiazolylamino)sulfonyl]phenyl]-

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N-Acetylsulfathiazole

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