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CAS 127254-12-0: Sitafloxacin

Formula:C19H18ClF2N3O3
InChI:InChI=1S/C19H18ClF2N3O3/c20-14-15-8(17(26)9(18(27)28)5-25(15)12-4-10(12)21)3-11(22)16(14)24-6-13(23)19(7-24)1-2-19/h3,5,10,12-13H,1-2,4,6-7,23H2,(H,27,28)/t10-,12+,13+/m0/s1
InChI key:InChIKey=PNUZDKCDAWUEGK-CYZMBNFOSA-N
SMILES:N[C@H]1C2(CN(C1)C=3C(Cl)=C4N(C=C(C(O)=O)C(=O)C4=CC3F)[C@H]5[C@@H](F)C5)CC2
Synonyms:
  • 3-Quinolinecarboxylic acid, 7-(7-amino-5-azaspiro[2.4]hept-5-yl)-8-chloro-6-fluoro-1-(2-fluorocyclopropyl)-1,4-dihydro-4-oxo-, [1R-[1α(S*),2α]]-
  • 3-Quinolinecarboxylic acid, 7-[(7S)-7-amino-5-azaspiro[2.4]hept-5-yl]-8-chloro-6-fluoro-1-[(1R,2S)-2-fluorocyclopropyl]-1,4-dihydro-4-oxo-
  • 5-Azaspiro[2.4]heptane, 3-quinolinecarboxylic acid deriv.
  • 7-[(4S)-4-Amino-6-azaspiro[2.4]heptan-6-yl]-8-chloro-6-fluoro-1-[(2S)-2-fluorocyclopropyl]-4-oxoquinoline-3-carboxylic acid
  • 7-[(7S)-7-Amino-5-azaspiro[2.4]hept-5-yl]-8-chloro-6-fluoro-1-[(1R,2S)-2-fluorocyclopropyl]-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid
  • 7-[(7S)-7-amino-5-azaspiro[2.4]hept-5-yl]-8-chloro-6-fluoro-1-[(1R,2S)-2-fluorocyclopropyl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
  • 7-[(7S)-7-amino-5-azaspiro[2.4]hept-5-yl]-8-chloro-6-fluoro-1-[(2S)-2-fluorocyclopropyl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
  • DU 6859a
  • Du 6859
  • Gracevit
  • Spifloxacin
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Found 11 products.
  • Ref: TR-DRE-A16970810AL-100

    1ml
    36.00€
  • Sitafloxacin 100 µg/mL in Acetonitrile

    Controlled Product
    CAS:
    Formula:C19H18ClF2N3O3
    Color and Shape:Single Solution
    Molecular weight:409.81

    Ref: 04-A16970810AL-100

    1ml
    To inquire
  • Sitafloxacin

    CAS:
    Formula:C19H18ClF2N3O3
    Color and Shape:White To Off-White Solid
    Molecular weight:409.82

    Ref: 4Z-S-079001

    5mg
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    10mg
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    25mg
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    50mg
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    100mg
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  • Ref: 7W-GA0080

    ne
    To inquire
  • Ref: IN-DA000WTZ

    1mg
    203.00€
    10mg
    550.00€
  • Sitafloxacin

    CAS:
    Formula:C19H18ClF2N3O3
    Color and Shape:Neat
    Molecular weight:409.81

    Ref: 04-C16970810

    50mg
    To inquire
  • Sitafloxacin-d4

    CAS:
    Formula:C19H14D4ClF2N3O3
    Color and Shape:White To Off-White Solid
    Molecular weight:413.84

    Ref: 4Z-S-079005

    5mg
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    10mg
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    25mg
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    50mg
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    100mg
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  • Sitafloxacin

    CAS:
    Sitafloxacin: potent broad-spectrum oral fluoroquinolone effective against resistant strains.
    Formula:C19H18ClF2N3O3
    Purity:99.2%
    Color and Shape:Solid
    Molecular weight:409.81

    Ref: TM-T6349L

    2mg
    42.00€
    5mg
    62.00€
    10mg
    89.00€
    25mg
    145.00€
    50mg
    212.00€
    100mg
    315.00€
    200mg
    469.00€
  • Sitafloxacin

    CAS:
    Sitafloxacin is an antibacterial agent belonging to the fluoroquinolone class of antibiotics, which is synthetically derived from chemical processes involving fluorinated quinolones. Its mode of action involves the inhibition of bacterial DNA gyrase and topoisomerase IV, enzymes crucial for bacterial DNA replication and transcription. By interfering with these enzymes, Sitafloxacin effectively hampers bacterial DNA synthesis, leading to the eventual demise of the bacterial cell. Sitafloxacin is primarily used for the treatment of a broad spectrum of bacterial infections, showing efficacy against both Gram-positive and Gram-negative pathogens. It is often utilized in the management of urinary tract infections, respiratory tract infections, and certain types of skin infections. Its broad-spectrum activity is particularly advantageous in tackling multi-drug resistant bacterial strains. This makes Sitafloxacin a valuable tool in the arsenal of antibiotics, especially in scenarios where resistance to other antibiotics is a concern. Researchers continue to study its pharmacokinetics and potential resistance mechanisms to maximize its therapeutic efficacy and minimize adverse effects.
    Formula:C19H18ClF2N3O3
    Purity:Min. 95%
    Color and Shape:Solid
    Molecular weight:409.81 g/mol

    Ref: 3D-FS103799

    5mg
    315.00€
    10mg
    357.00€
    25mg
    596.00€
  • Sitafloxacin

    CAS:
    Sitafloxacin
    Purity:≥98%
    Molecular weight:409.81g/mol

    Ref: 54-BUP09356

    1mg
    185.00€
    2mg
    254.00€
    5mg
    400.00€
    10mg
    763.00€
    25mg
    1,444.00€
    50mg
    2,709.00€
  • Sitafloxacin

    CAS:
    Formula:C19H18ClF2N3O3

    Ref: TR-DRE-C16970810

    50mg
    188.00€