
CAS 127254-12-0: Sitafloxacin
Formula:C19H18ClF2N3O3
InChI:InChI=1S/C19H18ClF2N3O3/c20-14-15-8(17(26)9(18(27)28)5-25(15)12-4-10(12)21)3-11(22)16(14)24-6-13(23)19(7-24)1-2-19/h3,5,10,12-13H,1-2,4,6-7,23H2,(H,27,28)/t10-,12+,13+/m0/s1
InChI key:InChIKey=PNUZDKCDAWUEGK-CYZMBNFOSA-N
SMILES:N[C@H]1C2(CN(C1)C=3C(Cl)=C4N(C=C(C(O)=O)C(=O)C4=CC3F)[C@H]5[C@@H](F)C5)CC2
Synonyms:- 3-Quinolinecarboxylic acid, 7-(7-amino-5-azaspiro[2.4]hept-5-yl)-8-chloro-6-fluoro-1-(2-fluorocyclopropyl)-1,4-dihydro-4-oxo-, [1R-[1α(S*),2α]]-
- 3-Quinolinecarboxylic acid, 7-[(7S)-7-amino-5-azaspiro[2.4]hept-5-yl]-8-chloro-6-fluoro-1-[(1R,2S)-2-fluorocyclopropyl]-1,4-dihydro-4-oxo-
- 5-Azaspiro[2.4]heptane, 3-quinolinecarboxylic acid deriv.
- 7-[(4S)-4-Amino-6-azaspiro[2.4]heptan-6-yl]-8-chloro-6-fluoro-1-[(2S)-2-fluorocyclopropyl]-4-oxoquinoline-3-carboxylic acid
- 7-[(7S)-7-Amino-5-azaspiro[2.4]hept-5-yl]-8-chloro-6-fluoro-1-[(1R,2S)-2-fluorocyclopropyl]-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid
- 7-[(7S)-7-amino-5-azaspiro[2.4]hept-5-yl]-8-chloro-6-fluoro-1-[(1R,2S)-2-fluorocyclopropyl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
- 7-[(7S)-7-amino-5-azaspiro[2.4]hept-5-yl]-8-chloro-6-fluoro-1-[(2S)-2-fluorocyclopropyl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
- DU 6859a
- Du 6859
- Gracevit
- Spifloxacin
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Found 11 products.
Sitafloxacin 100 µg/mL in Acetonitrile
CAS:Controlled ProductFormula:C19H18ClF2N3O3Color and Shape:Single SolutionMolecular weight:409.81Sitafloxacin
CAS:Formula:C19H18ClF2N3O3Color and Shape:White To Off-White SolidMolecular weight:409.823-Quinolinecarboxylic acid, 7-[(7S)-7-amino-5-azaspiro[2.4]hept-5-yl]-8-chloro-6-fluoro-1-[(1R,2S)-2-fluorocyclopropyl]-1,4-dihydro-4-oxo-
CAS:Formula:C19H18ClF2N3O3Purity:99%Color and Shape:SolidMolecular weight:409.8143Sitafloxacin-d4
CAS:Formula:C19H14D4ClF2N3O3Color and Shape:White To Off-White SolidMolecular weight:413.84Sitafloxacin
CAS:Sitafloxacin: potent broad-spectrum oral fluoroquinolone effective against resistant strains.Formula:C19H18ClF2N3O3Purity:99.2%Color and Shape:SolidMolecular weight:409.81Sitafloxacin
CAS:Sitafloxacin is an antibacterial agent belonging to the fluoroquinolone class of antibiotics, which is synthetically derived from chemical processes involving fluorinated quinolones. Its mode of action involves the inhibition of bacterial DNA gyrase and topoisomerase IV, enzymes crucial for bacterial DNA replication and transcription. By interfering with these enzymes, Sitafloxacin effectively hampers bacterial DNA synthesis, leading to the eventual demise of the bacterial cell. Sitafloxacin is primarily used for the treatment of a broad spectrum of bacterial infections, showing efficacy against both Gram-positive and Gram-negative pathogens. It is often utilized in the management of urinary tract infections, respiratory tract infections, and certain types of skin infections. Its broad-spectrum activity is particularly advantageous in tackling multi-drug resistant bacterial strains. This makes Sitafloxacin a valuable tool in the arsenal of antibiotics, especially in scenarios where resistance to other antibiotics is a concern. Researchers continue to study its pharmacokinetics and potential resistance mechanisms to maximize its therapeutic efficacy and minimize adverse effects.Formula:C19H18ClF2N3O3Purity:Min. 95%Color and Shape:SolidMolecular weight:409.81 g/mol