CAS 1276110-06-5: HS-173
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Found 6 products.
Imidazo[1,2-a]pyridine-3-carboxylic acid, 6-[5-[(phenylsulfonyl)amino]-3-pyridinyl]-, ethyl ester
CAS:Formula:C21H18N4O4SPurity:98%Color and Shape:SolidMolecular weight:422.457HS-173
CAS:HS-173 is an effective PI3Kα inhibitor (IC50: 0.8 nM).Formula:C21H18N4O4SPurity:99.33% - 99.64%Color and Shape:SolidMolecular weight:422.46Ethyl 6-(5-(Phenylsulfonamido)Pyridin-3-Yl)Imidazo[1,2-A]Pyridine-3-Carboxylate
CAS:Ethyl 6-(5-(Phenylsulfonamido)Pyridin-3-Yl)Imidazo[1,2-A]Pyridine-3-CarboxylatePurity:97%Molecular weight:422.46g/molHS-173
CAS:HS-173 is a synthetic nucleoside analog that has transcription-polymerase chain inhibitory activity. HS-173 inhibits the expression of genes by binding to the major groove of DNA and blocking the progression of transcription. This drug also induces autophagy to eliminate damaged or dysfunctional cells, as well as regulating cell proliferation and differentiation. In addition, HS-173 has been shown to have synergistic effects with epidermal growth factor (EGF) and radiation in hl-60 cells and monoclonal antibody against carcinoembryonic antigen in k562 cells.Formula:C21H18N4O4SPurity:Min. 95%Molecular weight:422.46 g/molHS-173
CAS:Controlled ProductApplications HS-173 is a potent PI3Kα inhibitor with anticancer activity. References Kim, O., et al.: J. Med. Chem., 54, 2455 (2011); Lee, H., et al.: Cancer Lett., 328, 152 (2013)Formula:C21H18N4O4SColor and Shape:NeatMolecular weight:422.46
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