5'-O-(Dimethoxytrityl)-2'-O-methylinosine is a modified nucleoside that plays a significant role in the field of nucleic acid chemistry, particularly in the synthesis of oligonucleotides. This compound features a purine base, inosine, which is modified at the 2' position with a methyl group, enhancing its stability and resistance to enzymatic degradation. The 5' position is protected by a dimethoxytrityl (DMT) group, which is commonly used in solid-phase oligonucleotide synthesis to prevent premature reactions during the synthesis process. The presence of the DMT group allows for selective deprotection, facilitating the stepwise assembly of nucleic acid sequences. This compound is typically used in research and therapeutic applications, including the development of antisense oligonucleotides and RNA interference technologies. Its structural modifications contribute to improved solubility and bioavailability, making it a valuable tool in molecular biology and genetic engineering. Overall, 5'-O-(Dimethoxytrityl)-2'-O-methylinosine exemplifies the advancements in nucleoside chemistry aimed at enhancing the efficacy of nucleic acid-based therapies.

5'-O-(DIMETHOXYTRITYL)-2'-O-METHYLINOSINE

128219-84-1: 5'-O-DMT-2'-O-Methyl-inosine

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5'-O-DMT-2'-O-methylinosine

Inosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl- (9CI)

Nucleoside Derivatives - 2’-Modified nucleosides,Protected nucleoside with NH2/OH open

CAS 128219-84-1: 5'-O-(DIMETHOXYTRITYL)-2'-O-METHYLINOSINE

5'-O-DMT-2'-O-methylinosine

Ref: 3D-ND08419

Inosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl- (9CI)

Ref: IN-DA000XW4

5'-O-(4,4-Dimethoxytrityl)-2'-O-methyl inosine

Ref: TM-TNU1560