CAS 130-01-8: senecionine
Formula:C18H25NO5
InChI:InChI=1S/C18H25NO5/c1-4-12-9-11(2)18(3,22)17(21)23-10-13-5-7-19-8-6-14(15(13)19)24-16(12)20/h4-5,11,14-15,22H,6-10H2,1-3H3/b12-4-/t11-,14-,15-,18-/m1/s1
InChI key:InChIKey=HKODIGSRFALUTA-JTLQZVBZSA-N
SMILES:O=C/1O[C@]2([C@@]3(N(CC2)CC=C3COC(=O)[C@](C)(O)[C@H](C)C\C1=C\C)[H])[H]
Synonyms:- (15Z)-12-hydroxysenecionan-11,16-dione
- (3Z,5R,6R,14aR,14bR)-3-Ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-5,6-dimethyl[1,6]dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione
- 12-Hydroxysenecionan-11,16-Dione
- Aureine
- NSC 89935
- Senecionan-11,16-dione, 12-hydroxy-
- Senecionin
- [1,6]Dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione, 3-ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-5,6-dimethyl-, (3Z,5R,6R,14aR,14bR)-
- [1,6]Dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione, 3-ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-5,6-dimethyl-, [5R-(3Z,5R*,6R*,14aR*,14bR*)]-
- Senecionine
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Found 15 products.
Senecionine 100 µg/mL in Methanol:Water
CAS:Controlled ProductFormula:C18H25NO5Color and Shape:Single SolutionMolecular weight:335.39[1,6]Dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione, 3-ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-5,6-dimethyl-, (3Z,5R,6R,14aR,14bR)-
CAS:Formula:C18H25NO5Purity:97.5%Color and Shape:SolidMolecular weight:335.3948Senecionine
CAS:Senecionine (Senecionin) is the hepatotoxic pyrrolizidine alkaloids isolated from Senecio vulgaris.Formula:C18H25NO5Purity:97.8% - 98.82%Color and Shape:SolidMolecular weight:335.39Senecionine
CAS:Natural alkaloidFormula:C18H25NO5Purity:≥ 98.0 % (HPLC)Color and Shape:PowderMolecular weight:335.4Senecionine
CAS:Senecionine analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.Formula:C18H25NO5Purity:(HPLC) ≥95%Color and Shape:PowderMolecular weight:335.41Senecionine
CAS:Senecionine is a n-oxide that is found in the plant Senecio jacobaea. It has been shown to have insecticidal, antiparasitic, and anticancer activity. The mechanism of senecionine's cytotoxicity is not well understood, but it may be due to its ability to cause mitochondrial dysfunction and cell lysis. Senecionine also binds to p2y receptors, which are a family of G protein-coupled receptors that are involved in inflammation and immunity. The binding of senecionine to these receptors leads to the activation of phospholipase C and inhibition of adenylate cyclase. This results in an increase in intracellular calcium levels and subsequent cell lysis.Formula:C18H25NO5Purity:Min. 95%Color and Shape:PowderMolecular weight:335.39 g/molSenecionine-D3
CAS:Controlled ProductFormula:C18H22D3NO5Color and Shape:White To BeigeMolecular weight:338.41
![[1,6]Dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione, 3-ethylidene-3,4,5,6,9,11,13,14,14a,14b-de…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA000TUW.jpg&w=3840&q=75)
