(S)-Cetirizine is an antihistamine commonly used to alleviate allergy symptoms such as sneezing, runny nose, and itching. It is the active enantiomer of cetirizine, which is a second-generation antihistamine derived from piperazine. This compound exhibits a high affinity for peripheral H1 receptors, effectively blocking the action of histamine, a key mediator in allergic reactions. (S)-Cetirizine is characterized by its relatively low sedative effects compared to first-generation antihistamines, making it suitable for daytime use. It is typically administered orally and is well-absorbed in the gastrointestinal tract. The substance is known for its favorable pharmacokinetic profile, including a long half-life, which allows for once-daily dosing. Additionally, (S)-Cetirizine is generally well-tolerated, with a low incidence of adverse effects, although some individuals may experience drowsiness or dry mouth. Its chemical structure includes a carboxylic acid group, contributing to its solubility and bioavailability. Overall, (S)-Cetirizine is an effective and widely used medication in the management of allergic conditions.

(S)-Cetirizine

130018-76-7: (S)-[2-[4-[(4-Chlorophenyl)-phenylmethyl]-1-piperazinyl]ethoxy]acetic Acid, Dextrocetirizin, Dextrocetirizine, (2-{4-[(S)-(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetic acid

CAS 130018-76-7: (S)-Cetirizine

(S)-Cetirizine-d4

Ref: 4Z-C-203

(S)-Cetirizine

Ref: 4Z-C-2072

Levocetirizine EP Impurity A

Ref: ST-EA-CP-L15033