8-Quinolinol, 7-bromo- is an organic compound characterized by the presence of a bromine atom at the 7-position of the quinoline ring system. This compound features a hydroxyl group (-OH) at the 8-position, which contributes to its classification as a quinolinol. It is typically a solid at room temperature and exhibits a pale yellow to brownish color. The presence of the bromine atom enhances its reactivity, making it useful in various chemical applications, including as a ligand in coordination chemistry and in the synthesis of other organic compounds. 8-Quinolinol derivatives are known for their biological activity, including antimicrobial and antifungal properties. The compound is soluble in organic solvents but has limited solubility in water, which is common for many quinoline derivatives. Safety precautions should be taken when handling this substance, as it may pose health risks upon exposure. Overall, 8-Quinolinol, 7-bromo- is a significant compound in both synthetic and medicinal chemistry.

8-Quinolinol, 7-bromo-

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7-Bromoquinolin-8-ol

7-Bromo-8-hydroxyquinoline is a structural analog of cisplatin, which is a cancer chemotherapy drug. It has been shown to be an effective microbicide that can kill bacteria and fungi in vitro. This compound has also been used as a potential antitumor agent. 7-Bromo-8-hydroxyquinoline is synthesized by reacting 2 equivalents of bromine with 4 equivalents of sodium hydroxide, followed by the addition of 8 equivalents of hydroxylamine hydrochloride in water at room temperature. The product crystallizes as white needles that are soluble in dimethylamine or water. 7-Bromo-8-hydroxyquinoline has been shown to have antitumor activity against human alveolar cells, which may be due to its ability to inhibit DNA synthesis, protein synthesis, and cell division.

CAS 13019-32-4: 8-Quinolinol, 7-bromo-

7-Bromoquinolin-8-ol

Ref: 10-F435535

8-Quinolinol, 7-bromo-

Ref: IN-DA000U49

7-Bromo-8-hydroxyquinoline

Ref: 3D-NAA01932

7-Bromoquinolin-8-Ol

Ref: 54-OR1012065