CAS 13081-18-0: Ethyl 3,3,3-trifluoro-2-oxopropanoate

Stability Moisture Sensitive Applications Trifluoropyruvic Acid Ethyl Ester is used as a reagent in the preparation of potential biologically active compounds such as in the highly enantioselective organocatalytic hydroxyalkylation of indoles. References Toeroek, B. et al.: Angew. Chem. Int. Ed., 44, 3086 (2005); Wolf, C. et al.: Adv. Synth. Cat., 353, 760 (2011);

Trifluoropyruvic acid ethyl ester is a synthetic compound and an enantiopure ligand for coordination chemistry. It is activated by the addition of hydroxyl groups to the molecule, which can be achieved with hydrochloric acid. Trifluoropyruvic acid ethyl ester has been shown to form stable complexes with metal ions, such as copper and zinc. This complex has been shown to bind to receptors in biological systems, including non-steroidal anti-inflammatory agents. Trifluoropyruvic acid ethyl ester binds to receptors on cell membranes by intermolecular hydrogen bonding between the phenolic hydroxyl group and the receptor's aromatic ring system, which induces conformational changes in the receptor protein that leads to its activation or inhibition.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Ethyl trifluoropyruvate acts as a building block in synthetic chemistry for the synthesis of fluorine containing compounds. It is also used as a reagent for the preparation of potential biologically active compounds like highly enantioselective organocatalytic hydroxyalkylation of indoles. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Ethyl trifluoropyruvate