CAS: 1309048-48-3

Clindamycin-2,4-diphosphate is a phosphorylated derivative of the antibiotic clindamycin, which is a semi-synthetic lincosamide antibiotic originally derived from Streptomyces lincolnensis. Its mode of action involves the inhibition of bacterial protein synthesis by binding to the 50S ribosomal subunit, thereby preventing peptide chain elongation during translation. This mechanism effectively disrupts protein production in susceptible bacteria, leading to their growth inhibition or death. The phosphorylated form, Clindamycin-2,4-diphosphate, is of particular interest in the scientific community for its enhanced solubility and potential use in research applications regarding bacterial resistance studies. It is typically employed in laboratory settings to study the pharmacokinetics of clindamycin derivatives and their interactions with various bacterial strains. Its applications also extend to developmental research of new antibiotic therapies targeting resistant bacterial pathogens.