CAS 131-53-3: 2,2′-Dihydroxy-4-methoxybenzophenone

Dioxybenzone

Ketone-phenols and ketones with other oxygen function

Stability Hygroscopic Applications Dioxybenzone-d3 is an isotopic analog of Dioxybenzone (D486365), a compound used in sunscreen formulations to block out UVB and UVA harmful rays. References Baumgartner, V. et al.: J. Planar. Chrom. Modern. TLC., 22, 19 (2009); Kunisue, T. et al.: Anal. Meth., 2, 707 (2010);

Dioxybenzone (Benzophenone-8) is an organic agent that blocks UVB and short-wave UVA ultraviolet radiation.

2,2'-Dihydroxy-4-methoxybenzophenone (DHMB) is a chemical compound used in the manufacturing of sunscreens. It is also used as an antioxidant and antiinflammatory agent in topical preparations. The genotoxic effects of DHMB are well documented, but it is unclear whether these effects are due to UV radiation or other mechanisms. DHMB has been shown to be toxic to cells in vivo and in vitro. There have been reports of skin cancer developing on the ears of rats following chronic exposure to this chemical. DHMB binds to the estrogen receptor, which may be responsible for its genotoxic activity. This chemical has also been shown to inhibit the growth of bacteria such as Pseudomonas aeruginosa and Escherichia coli by binding with fatty acids on the cell membrane surface. DHMB is used for wastewater treatment because it can bind with heavy metals and remove them from water sources.

2,2'-Dihydroxy-4-methoxybenzophenone