CAS 1314116-53-4: Clopidogrel-β-<span class="text-smallcaps">D</span>-glucuronide
Formula:C21H22ClNO8S
InChI:InChI=1S/C21H22ClNO8S/c22-12-4-2-1-3-11(12)14(23-7-5-13-10(9-23)6-8-32-13)20(29)31-21-17(26)15(24)16(25)18(30-21)19(27)28/h1-4,6,8,14-18,21,24-26H,5,7,9H2,(H,27,28)/t14-,15-,16-,17+,18-,21-/m0/s1
InChI key:InChIKey=TUBQAJBXTWIXFX-CLCCAKIRSA-N
SMILES:[C@H](C(O[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O)=O)(N2CC3=C(CC2)SC=C3)C4=C(Cl)C=CC=C4
Synonyms:- Clopidogrel-β-D-glucuronide
- β-D-Glucopyranuronic acid, 1-[(αS)-α-(2-chlorophenyl)-6,7-dihydrothieno[3,2-c]pyridine-5(4H)-acetate]
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Found 6 products.
Clopidogrel-β-D-glucuronide ((2S,3S,4S,5R,6S)-6-((S)-2-(2-chlorophenyl)-2-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetoxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid)
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFormula:C21H22ClNO8SColor and Shape:White Off-White SolidMolecular weight:483.07547Clopidogrel acyl glucuronide
CAS:Clopidogrel is a prodrug that is metabolized to the active form, clopidogrel acyl glucuronide (CPG). The glucuronide conjugate of CPG is excreted in urine and can be used as a potential biomarker for drug interactions. Clopidogrel acyl glucuronide is an inhibitor of CYP2C19, CYP1A2, and CYP3A4 which may lead to drug-drug interactions. Clopidogrel also inhibits uptake by P-glycoprotein and efflux by MRPs. The uptake of CPG in the liver cells from the blood stream is low due to its high affinity for proteins such as albumin. This makes it difficult to measure plasma concentrations of CPG and its metabolites. However, CPG can be detected in human liver microsomes using liquid chromatography with tandem mass spectrometry (LC-MS/MS) analysis. The metaboliteFormula:C21H22ClNO8SPurity:Min. 95%Molecular weight:483.92 g/molClopidogrel Acyl-beta-D-glucuronide
CAS:Controlled ProductFormula:C21H18ClD4NO8SColor and Shape:NeatMolecular weight:483.92Clopidogrel Acyl-Beta-D-glucuronide
CAS:Controlled ProductApplications A metabolite of Clopidogrel.Formula:C21H22ClNO8SColor and Shape:NeatMolecular weight:483.92Clopidogrel Acyl-β-D-Glucuronide
CAS:Formula:C21H22ClNO8SColor and Shape:White To Off-White SolidMolecular weight:483.92
