CAS 133-67-5: Trichlormethiazide
Formula:C8H8Cl3N3O4S2
InChI:InChI=1S/C8H8Cl3N3O4S2/c9-3-1-4-6(2-5(3)19(12,15)16)20(17,18)14-8(13-4)7(10)11/h1-2,7-8,13-14H,(H2,12,15,16)
InChI key:InChIKey=LMJSLTNSBFUCMU-UHFFFAOYSA-N
SMILES:O=S1(=O)C=2C(NC(C(Cl)Cl)N1)=CC(Cl)=C(S(N)(=O)=O)C2
Synonyms:- 3-Dichloromethyl-6-chloro-7-sulfamoyl-3,4-dihydro-1,2,4-benzothiadiazine-1,1-dioxide
- 3-Dichloromethyl-6-chloro-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine 1,1-dioxide
- 3-Dichloromethylhydrochlorothiazide
- 6-Chloro-3-(dichloromethyl)-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
- 6-Chloro-3-(dichloromethyl)-3,4-dihydro-7-sulfamyl-1,2,4-benzothiadiazine-1,1-dioxide
- 6-Chloro-3-dichloromethyl-3, 4-dihydro-2H-1, 2, 4-benzothiadiazine-7-sulfonamide-1, 1-dioxide
- 6-Chloro-3-dichloromethyl-3,4-dihydro-7-sulfamoyl-2H-1,2,4-benzothiadiazine 1,1-dioxide
- Achletin
- Anatran
- Anistadin
- Aponorin
- See more synonyms
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Found 14 products.
Trichlormethiazide
CAS:Controlled ProductFormula:C8H8Cl3N3O4S2Color and Shape:NeatMolecular weight:380.66Trichloromethiazide
CAS:Formula:C8H8Cl3N3O4S2Purity:>99.0%(T)Color and Shape:White to Almost white powder to crystalMolecular weight:380.64Trichlormethiazide
CAS:Trichlormethiazide (Naqua) is a short-acting, 3-dichloromethyl derivative of hydrochlorothiazide, belonging to the class of thiazide diuretics.Formula:C8H8Cl3N3O4S2Purity:98.80% - 99.54%Color and Shape:SolidMolecular weight:380.66Trichlormethiazide
CAS:Sulfonamides used as drugsFormula:C8H8Cl3N3O4S2Color and Shape:White PowderMolecular weight:380.67 g/molTrichloromethiazide
CAS:Trichloromethiazide is a hypoglycemic drug that lowers the blood glucose level by inhibiting the activity of enzymes involved in carbohydrate metabolism. Trichloromethiazide has been shown to inhibit the activity and synthesis of methyl transferase, which is an enzyme that catalyzes the transfer of methyl groups from S-adenosylmethionine (SAM) to erythrocyte membrane proteins. It also acts as an inhibitor for dapagliflozin, which is a drug used for diabetes treatment. Trichloromethiazide is absorbed through the gastrointestinal tract and is excreted in urine unchanged. The absorption enhancer sodium dodecyl sulfate (SDS) facilitates this process. This drug has been found to bind to receptor sites on cells, which may be related to its anti-inflammatory properties.Formula:C8H8Cl3N3O4S2Purity:Min. 95%Molecular weight:380.64 g/molTrichlormethiazide
CAS:Controlled ProductApplications Trichlormethiazide, is a diuretic, having similar properties as Hydrochlorothiazide (H714560). It is used for the treatment of oedema (including that which is associated with heart failure, hepatic cirrhosis and corticosteroid therapy) and hypertension. References Imamura, T., et al.: International Heart J., 54(1), 48 (2013); Takahashi, Y., et al.: Cardiovas. Diabetology, 10(1), 45 (2011);Formula:C8H8Cl3N3O4S2Color and Shape:NeatMolecular weight:380.66
