5-(2-Bromoethyl)-benzofuran is an organic compound characterized by the presence of a benzofuran moiety, which consists of a fused benzene and furan ring. The compound features a bromoethyl substituent at the 5-position of the benzofuran, introducing a bromine atom and an ethyl group into its structure. This substitution can influence the compound's reactivity, solubility, and potential applications in organic synthesis or medicinal chemistry. Typically, compounds like this may exhibit biological activity, making them of interest in pharmaceutical research. The presence of the bromine atom can also facilitate further chemical modifications through nucleophilic substitution reactions. Additionally, the compound's physical properties, such as melting point, boiling point, and solubility, would depend on its molecular structure and the interactions between its functional groups. Safety data and handling precautions are essential when working with this compound, particularly due to the presence of bromine, which can be hazardous. Overall, 5-(2-Bromoethyl)-benzofuran represents a versatile structure in organic chemistry with potential applications in various fields.

5-(2-Bromoethyl)-benzofuran

133034-06-7: Benzofuran, 5-(2-bromoethyl)-, 5-(2-Bromoethyl)benzo[2,3-b]furan

Applications 5-(2-Bromoethyl)benzofuran is an impurity of Darifenacin (D193400), a drug that blocks the M3 muscarinic acetylcholine receptor and used to treat urinary incontinence. 5-(2-Bromoethyl)benzofuran can also be used to prepare 3,6-disubstituted azabicyclo[3.1.0]hexane derivatives as muscarinic receptor antagonists.
References Mehta, A., et al.: PCT Int. Appl. WO 2004052857 A1 20040624  (2004); Beaumont, K.C., et al.: Xenobiotica, 28, 63 (1998); Chapple, C.R., et al.: Expert Opin. Invest. Drugs, 13, 1493 (2004); Haab, F., et al.: Eur. Urol., 45, 420 (2004)


CAS 133034-06-7: 5-(2-Bromoethyl)-benzofuran

5-(2-Bromoethyl)benzofuran

Ref: TR-B680450

5-(2-bromoethyl)-1-benzofuran

Ref: 3D-IFA03406

5-(2-Bromoethyl)benzofuran

Ref: ST-EA-CP-D11027

Darifenacin Impurity 13

Ref: 4Z-D-1737