CAS 133082-19-6: 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 2-[4-(diphenylmethyl)-1-piperazinyl]ethyl methyl ester, (4R)-
Formula:C35H38N4O6
InChI:InChI=1S/C35H38N4O6/c1-24-30(34(40)44-3)32(28-15-10-16-29(23-28)39(42)43)31(25(2)36-24)35(41)45-22-21-37-17-19-38(20-18-37)33(26-11-6-4-7-12-26)27-13-8-5-9-14-27/h4-16,23,32-33,36H,17-22H2,1-3H3/t32-/m1/s1
InChI key:InChIKey=ANEBWFXPVPTEET-JGCGQSQUSA-N
SMILES:C(OCCN1CCN(C(C2=CC=CC=C2)C3=CC=CC=C3)CC1)(=O)C=4[C@@H](C(C(OC)=O)=C(C)NC4C)C5=CC(N(=O)=O)=CC=C5
Synonyms:- (-)-Manidipine
- (4R)-1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 2-[4-(Diphenylmethyl)-1-piperazinyl]ethyl Methyl Ester
- 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 2-[4-(diphenylmethyl)-1-piperazinyl]ethyl methyl ester, (4R)-
- 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 2-[4-(diphenylmethyl)-1-piperazinyl]ethyl methyl ester, (4R)- (9CI)
- 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 2-[4-(diphenylmethyl)-1-piperazinyl]ethyl methyl ester, (R)-
- O3-[2-(4-benzhydrylpiperazin-1-yl)ethyl] O5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
- R-(-)-Manidipine
Sort by
Found 6 products.
3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 2-[4-(diphenylmethyl)-1-piperazinyl]ethyl methyl ester, (4R)- (9CI)
CAS:Formula:C35H38N4O6Molecular weight:610.6994R-(-)-Manidipine Hydrochloride
CAS:Controlled ProductFormula:C35H38N4O6·HClColor and Shape:NeatMolecular weight:647.16R-(-)-Manidipine
CAS:R-(-)-Manidipine is a chiral compound that is metabolized in the body to form two enantiomers, (+)- and (-)-manidipine. The pharmacokinetic study of R-(-)-Manidipine was conducted by comparing the plasma concentrations of the racemic mixture with those of the individual enantiomers. The diastereomeric ratios were determined by analyzing plasma samples using a mass spectrometer and reaction monitoring. The pharmacokinetic study showed that both enantiomers have antihypertensive activity, but (-)-manidipine has higher potency than (+)-manidipine.Formula:C35H38N4O6Purity:Min. 95%Molecular weight:610.7 g/mol
