Uridine, 2'-O-2-propenyl- is a modified nucleoside that features a uridine base with a propenyl group attached to the 2' position of the ribose sugar. This modification can influence the molecule's biological activity, stability, and interaction with nucleic acids. The presence of the propenyl group may enhance its potential as a therapeutic agent or as a tool in molecular biology. Uridine itself is a pyrimidine nucleoside composed of a uracil base linked to a ribose sugar, playing a crucial role in RNA synthesis and metabolism. The modification at the 2' position can affect the nucleoside's hydrogen bonding capabilities and its overall conformation, potentially impacting its incorporation into RNA and its interactions with various enzymes and proteins. As a chemical entity, it is important to consider its solubility, reactivity, and stability under physiological conditions, which can vary based on the specific structural modifications present. Overall, Uridine, 2'-O-2-propenyl- represents a valuable compound in the study of nucleoside analogs and their applications in biochemistry and pharmacology.

Uridine, 2'-O-2-propenyl-

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2'-O-Allyluridine is a nucleoside analogue that contains a 2'-hydroxyl group and an allyl group. It is synthesized from the nucleoside uridine by the process of allylation. The regiospecificity of the allylation reaction has been analysed and it has been found that the amino function on the uridine reacts with an allylic hydrogen bond to form 2'-O-allyluridine. The synthesis of 2'-O-allyluridine was successful in laboratory conditions, but not under physiological conditions. Research into this compound is still ongoing as it may have potential applications in the treatment of various diseases, such as cancer.

CAS 133766-24-2: Uridine, 2'-O-2-propenyl-

2'-O-Allyluridine

Ref: 3D-NA06678