CAS 1338-41-6: Sorbitan, monooctadecanoate

Sorbitan monostearate is a lipid-soluble compound that is used as a surfactant and emulsifier in food products. It has been found to be nontoxic when administered at concentrations up to 5000 mg/kg of body weight for 28 days. Sorbitan monostearate has been shown to be nontoxic in vitro, but the long-term toxicity of this compound has not been established. Sorbitan monostearate also exhibits hydrogen bonding interactions with calcium pantothenate, sodium salts, and coumarin derivatives. The model system used was an artificial membrane composed of chitosan quaternary ammonium and monolaurate. This study found that sorbitan monostearate is able to permeabilize the membrane at an optimum concentration.

Applications Sorbitan is a surfactants used for the preparation in α-Tocopherol-loaded niosome. A separation improvers for the separation of fatty acid methyl ester (FAME) mixtures. References Basiri, L., et al.: Food Chem., 221, 620-628 (2017); Abe, M., Fuel.: 190, 351-358 (2017);

Span? 60

Sorbitan monostearate is an ester of stearic acid and sorbitan (a sorbitol derivative), it is also sometimes referred to as a synthetic wax.