CAS 13395-02-3: Aristolactam
Formula:C17H11NO4
InChI:InChI=1S/C17H11NO4/c1-20-12-4-2-3-8-9(12)5-11-14-10(17(19)18-11)6-13-16(15(8)14)22-7-21-13/h2-6H,7H2,1H3,(H,18,19)
InChI key:InChIKey=MXOKGWUJNGEKBH-UHFFFAOYSA-N
SMILES:O=C1C=2C3=C(C=4C(C=C3N1)=C(OC)C=CC4)C5=C(C2)OCO5
Synonyms:- 8-Methoxybenzo[f]-1,3-benzodioxolo[6,5,4-cd]indol-5(6H)-one
- 8-methoxy[1,3]benzodioxolo[6,5,4-cd]benzo[f]indol-5(6H)-one
- Aristolactam
- Aristololactam
- Aristololactam I
- Benzo[f]-1,3-benzodioxolo[6,5,4-cd]indol-5(6H)-one, 8-methoxy-
- NSC 87406
- Aristolactam I
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Found 8 products.
Aristolactam
CAS:Aristolactam is a naturally occurring alkaloid, which is derived from the Aristolochia genus of plants. This compound belongs to a class of heterocyclic aromatic compounds known for their intricate structures and biological activities. The biosynthesis of aristolactam occurs within plants primarily as a defense mechanism against herbivores and pathogens. The mode of action of aristolactam involves intercalation with DNA, disrupting cellular processes and potentially leading to apoptosis in cancerous cells. This intercalation hinders the progression of the cell cycle, thereby exerting cytotoxic effects that have been explored for therapeutic purposes. In scientific research, aristolactam has garnered interest due to its potential applications in oncology. Studies have been conducted to evaluate its efficacy as an anti-cancer agent, particularly in targeting resistant malignancies. Furthermore, understanding its action at the molecular level is crucial for developing novel chemotherapeutic strategies. Despite its potential, caution is advised in handling aristolactam, as compounds from Aristolochia have been associated with nephrotoxic effects. Continued research is essential to delineate its pharmacological profiles and optimize its therapeutic windows.Formula:C17H11NO4Purity:Min. 95%Color and Shape:Yellow SolidMolecular weight:293.27 g/molAristolactam
CAS:LactamsFormula:C17H11NO4Purity:≥ 95.0 % (HPLC)Color and Shape:PowderMolecular weight:293.28Aristolactam I
CAS:Aristolactam I (Aristololactum) has cytotoxic potency, mediated through the induction of apoptosis in a caspase 3-dependent pathway.Formula:C17H11NO4Purity:98.98% - 99.63%Color and Shape:SolidMolecular weight:293.27Ref: TM-T3S1227
1mg60.00€5mg140.00€10mg216.00€25mg369.00€50mg545.00€100mg775.00€1mL*10mM (DMSO)175.00€
