CAS 134-83-8: 4-Chlorobenzhydryl chloride

4-Chlorobenzhydryl chloride is a chemical compound that can be found in environmental pollution and in the pharmacopoeias of many countries. It is used to prepare samples for clinical studies, such as meclozine or cetirizine. 4-Chlorobenzhydryl chloride can also be found in wastewater from industries that use chlorinated hydrocarbons. In addition, it can be found in emissions from coal-fired power plants and chemical plants. 4-Chlorobenzhydryl chloride has been shown to cause cancer when administered to laboratory animals at high doses. This drug substance may also have antihistamine properties because it contains piperazine, which is an active ingredient in some antihistamines.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications 1-Chloro-4-(chlorophenylmethyl)benzene is used in the synthesis of novel benzhydrylpiperazine derivatives as cytotoxic compounds in the treatment of various cancers. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Gurdal, E. et al.: Drug Res., 63, 121 (2013); Yarim, M. et al.: Int. J. Mol. Sci., 13, 8071 (2013);

4-Chlorobenzhydryl chloride