RKI-1447, identified by its CAS number 1342278-01-6, is a chemical compound that has garnered attention in the field of medicinal chemistry, particularly for its potential therapeutic applications. It is classified as a small molecule inhibitor, specifically targeting certain pathways involved in disease processes. The compound exhibits a unique structure that contributes to its biological activity, often characterized by specific functional groups that enhance its interaction with biological targets. RKI-1447 has been studied for its efficacy in modulating cellular mechanisms, which may include anti-inflammatory or anti-cancer properties. Its pharmacokinetic profile, including absorption, distribution, metabolism, and excretion (ADME), is crucial for determining its suitability for clinical use. Additionally, safety and toxicity assessments are essential components of its evaluation in preclinical and clinical studies. Overall, RKI-1447 represents a promising candidate in drug development, with ongoing research aimed at elucidating its full therapeutic potential and mechanism of action.

RKI-1447

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RKI-1447 is a potent inhibitor of ROCK1 and ROCK2. It has anti-invasive and antitumor activities.

RKI-1447 is a potent inhibitor of ROCK1 and ROCK2, with IC50 of 14.5 nM and 6.2

Applications RKI-1447 is a potent and selective ROCK1 and ROCK2 inhibitor with significant anti-invasive and anti-tumor activies.
References Patel, R.A., et al.: Cancer Res., 72, 5025 (2012); Pireddu, R., et al.: Med. Chem. Comm., 3, 699 (2012)


CAS 1342278-01-6: RKI-1447

RKI-1447

Ref: 54-BUP17143

RKI-1447

Ref: TM-T1898

RKI-1447

Ref: 3D-BR172011

RKI-1447

Ref: TR-R550000

RKI1447

Ref: IN-DA009CEL

RKI-1447

Ref: 10-F390268