N-(2-Hydroxy-4-methylphenyl)acetamide, also known as paracetamol or acetaminophen, is an organic compound characterized by its aromatic structure and functional groups. It features a hydroxyl group (-OH) and an acetamide group (-NHCOCH3) attached to a phenyl ring, which contributes to its solubility in water and organic solvents. This compound is typically a white crystalline solid with a melting point that varies depending on purity. It is known for its analgesic and antipyretic properties, making it a common over-the-counter medication for pain relief and fever reduction. The compound exhibits moderate stability under normal conditions but can degrade when exposed to extreme temperatures or moisture. Its solubility in water is influenced by pH, and it is often formulated in various pharmaceutical preparations. Safety data indicates that while generally safe at recommended doses, excessive consumption can lead to hepatotoxicity. Overall, N-(2-Hydroxy-4-methylphenyl)acetamide is a widely used and studied compound in both medicinal chemistry and pharmacology.

N-(2-Hydroxy-4-methylphenyl)acetamide

13429-10-2: 2-Acetamido-5-methylphenol, 3-Methyl-6-acetamidophenol, 5-Methyl-2-acetamidophenol, Acetamide, N-(2-hydroxy-4-methylphenyl)-, N-(2-hydroxy-4-methylphenyl)acetamide, p-Acetotoluidide, 2′-hydroxy-

2-Acetamido-5-Methylphenol

N-(2-hydroxy-4-methylphenyl)acetamide

2'-HYDROXY-P-ACETOTOLUIDIDE, 98

N-(2-hydroxy-4-methylphenyl)acetamide is a chemical compound that is used as an intermediate in the synthesis of other pharmaceutical drugs. It has been shown to have a high degree of intramolecular hydrogen bonding, which was confirmed by spectroscopy and through the use of NMR. The activation energy for this reaction is estimated to be 43.5 kJ/mol, which makes it a very exothermic reaction. This reaction has also been shown to have an intramolecular hydrogen bond between the hydroxyl group and the carboxylic acid group.

CAS 13429-10-2: N-(2-Hydroxy-4-methylphenyl)acetamide

2-Acetamido-5-Methylphenol

Ref: 54-OR1028492

N-(2-hydroxy-4-methylphenyl)acetamide

Ref: 10-F311544

2'-HYDROXY-P-ACETOTOLUIDIDE, 98

Ref: IN-DA009DUI

N-(2-Hydroxy-4-methylphenyl)acetamide

Ref: 3D-FH117058