CAS 134448-10-5: L-trans-Epoxysuccinyl-Ile-Pro-OH propylamide
Formula:C18H29N3O6
InChI:InChI=1/C18H29N3O6/c1-4-8-19-15(22)13-14(27-13)16(23)20-12(10(3)5-2)17(24)21-9-6-7-11(21)18(25)26/h10-14H,4-9H2,1-3H3,(H,19,22)(H,20,23)(H,25,26)
SMILES:CCCN=C(C1C(C(=NC(C(C)CC)C(=O)N2CCCC2C(=O)O)O)O1)O
Synonyms:- Ca 074
- N-(3-Propylcarbamoyloxirane-2-carbonyl)-isoleucyl-proline
- L-Proline, 1-(N-((3-((propylamino)carbonyl)oxiranyl)carbonyl)-L-isoleucyl)-, (2S-trans)-
- N-{[(3S)-3-(propylcarbamoyl)oxiran-2-yl]carbonyl}-L-isoleucyl-L-proline
- N-{[3-(propylcarbamoyl)oxiran-2-yl]carbonyl}isoleucylproline
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Found 7 products.
CA-074
CAS:CA-074 is a research tool that can be used to study protein interactions. CA-074 is a small, synthetic peptide and a potent inhibitor of the ion channel TRPC1. It has been shown to inhibit the calcium currents in HEK293 cells expressing TRPC1 channels. CA-074 inhibits the kinase activity of PLCγ2, which leads to reduced phosphoinositide levels and a decrease in cell proliferation. CA-074 also inhibits PKCδ and PKCε, which are members of the protein kinase C family. The inhibition of these enzymes by CA-074 causes an increase in the intracellular concentration of diacylglycerol (DAG) and inositol triphosphate (IP3). These two molecules are involved in G protein signaling pathways that regulate cell proliferation, differentiation, and survival.Formula:C18H29N3O6Purity:Min. 95%Molecular weight:383.44 g/molL-trans-Epoxysuccinyl-Ile-Pro-OH propylamide
CAS:Inhibitor of cathepsin BFormula:C18H29N3O6Purity:Min. 95%Molecular weight:383.44 g/molCA 074
CAS:CA 074 is a potent inhibitor of cathepsin B with a Ki value of 2 to 5 nM.CA 074 inhibits ischemic hippocampal neuronal death in primates and attenuatesFormula:C18H29N3O6Purity:97.80%Color and Shape:SolidMolecular weight:383.44Ref: TM-T21509
1mg80.00€5mg210.00€10mg329.00€25mg660.00€50mg917.00€100mg1,216.00€1mL*10mM (DMSO)177.00€L-trans-Epoxysuccinyl-Ile-Pro-OH propylamide
CAS:CA074, a potent inhibitor specific for cathepsin B in vitro (IC₅₀= 2.24 nM for rat liver cathepsin B) and in vivo.Formula:C18H29N3O6Purity:98.3%Molecular weight:383.45
