Pyridine-4-sulfonyl chloride, with the CAS number 134479-04-2, is an aromatic sulfonyl chloride derived from pyridine. It features a pyridine ring substituted at the 4-position with a sulfonyl chloride group, which imparts distinct chemical properties. This compound is typically a colorless to pale yellow liquid and is known for its strong reactivity due to the presence of the sulfonyl chloride functional group. It is commonly used as a reagent in organic synthesis, particularly for the introduction of sulfonyl groups into various substrates, facilitating the formation of sulfonamides and other derivatives. Pyridine-4-sulfonyl chloride is also utilized in the preparation of pharmaceuticals and agrochemicals. Due to its reactive nature, it must be handled with care, as it can release toxic fumes upon contact with moisture or water, leading to the formation of hydrochloric acid and other byproducts. Proper safety precautions, including the use of personal protective equipment and working in a well-ventilated area, are essential when working with this compound.

pyridine-4-sulfonyl chloride

Pyridine-4-sulfonyl chloride is a chiral, enantiomerically pure compound that can be synthesized by the cyclocondensation of 4-aminopyridine and sulfuryl chloride. The x-ray analysis of the single crystals obtained from this synthesis has revealed the molecular structure of this compound. Pyridine-4-sulfonyl chloride is an analog of pyridine, with a sulfonyl group attached to one of its carbon atoms. This chlorinated compound is also a good nucleophile, which makes it useful as a catalyst for certain reactions.

CAS 134479-04-2: pyridine-4-sulfonyl chloride

Pyridine-4-sulfonyl chloride

Ref: 3D-FP148977

Vonoprazan Impurity 43

Ref: 4Z-V-051045

Pyridine-4-sulfonyl chloride

Ref: 10-F616996